ASSESSING SOURCES OF VARIABILITY IN MICROARRAY GENE EXPRESSION DATA

Experiments using microarrays abound in genomic research, yet one factor remains in question.Without replication, how much stock can we put into the findings of microarray Egg Cups experiments? In addition, there is a growing desire to integrate microarray data with other molecular databases.To accomplish this in a scientifically acceptable manner,

Apoptosis is an important defense mechanism mounted by the immune system to control virus replication.Hence, cytomegaloviruses (CMV) evolved and acquired numerous anti-apoptotic genes.The product of the human CMV (HCMV) UL36 gene, pUL36 (also known as vICA), binds to pro-caspase-8, thus inhibiting death-receptor apoptosis and enabling viral replica